Neurodegeneration, Huntington-Center NRW
Neurologische Klinik
Medizinische Fakultät
Universitätsklinikum St. Josef- und St. Elisabeth- Hospital
Gudrunstr. 56
44791 Bochum
Tel:
+49 (0)234 509-6405
Email:
carsten.saft@ruhr-uni-bochum.de
Huntington-Krankheit (Behandlung, Biomarker), Bewegungsstörungen
Saft, C. (2022). Huntington’s disease: disappointments and new beginnings. Lancet Neurology, 21(7), 582–584. https://doi.org/10.1016/s1474-4422(22)00189-2
Pinto, R. J., Arning, L., Giordano, J., Razghandi, P., Andrew, M. A., Gillis, T., Correia, K., Mysore, J. S., Urtubey, D. M. G., Parwez, C. R., Von Hein, S. M., Clark, H. L., Nguyen, H. P., Förster, E., Beller, A., Jayadaev, S., Keene, C. D., Bird, T. D., Lucente, D., Saft, C., . . . Wheeler, V. C. (2020). Patterns of CAG repeat instability in the central nervous system and periphery in Huntington’s disease and in spinocerebellar ataxia type 1. Human Molecular Genetics, 29(15), 2551–2567. https://doi.org/10.1093/hmg/ddaa139
Tabrizi, S. J., Leavitt, B. R., Landwehrmeyer, G. B., Wild, E. J., Saft, C., Barker, R. A., Blair, N. F., Craufurd, D., Priller, J., Rickards, H., Rosser, A., Kordasiewicz, H. B., Czech, C., Swayze, E. E., Norris, D. A., Baumann, T., Gerlach, I., Schobel, S. A., Paz, E., . . . Lane, R. M. (2019). Targeting Huntingtin Expression in Patients with Huntington's Disease. The New England Journal of Medicine, 380(24), 2307–2316. https://doi.org/10.1056/nejmoa1900907
Van Well, E. M., Bader, V., Patra, M., Sánchez-Vicente, A., Meschede, J., Furthmann, N., Schnack, C., Blusch, A., Longworth, J., Petrasch-Parwez, E., Haass, C., Arzberger, T., Trümbach, D., Angersbach, L., Showkat, C., Sehr, D. A., Berlemann, L. A., Goldmann, P. L., Clement, A. M., Saft, C., . . . Winklhofer, K. F. (2019). A protein quality control pathway regulated by linear ubiquitination. The EMBO Journal, 38(9). https://doi.org/10.15252/embj.2018100730
Saft, C. (2017). Identifying modifiers of Huntington’s disease progression. Lancet Neurology. https://doi.org/10.1016/s1474-4422(17)30179-5