Department of Neurophysiology
Faculty of Medicine
Ruhr University Bochum
Universitätsstr. 150
44801 Bochum
Room:
MA 4/150
Phone:
+49 (0)234 32-27350
Email:
eysel@ruhr-uni-bochum.de
'Functional Specificity and Plasticity in the Mature Visual System.'
The visual system is my central field of research, linked to the long-standing aim of understanding the cortical contributions to the functional specificity of cells in the visual cortex and characterizing effects and mechanisms of lesion-induced plasticity in the visual system. My experimental models are small, localized chemical and laser lesions, and localized activation and inactivation at different levels of the afferent visual system. My current main interest is the study of spatiotemporal dynamics of plasticity following retina and cortex lesions.
As a senior professor (emeritus), I do not operate my own laboratory. My research is done in collaborations, to which I contribute my expertise, within the RDN (with the Institute of Neuroinformatics as well as the Chair of Neurophysiology) and outside the RUB (MPI Martinsried, KU Leuven, Nencki Institute Warsaw, University of Melbourne) where I contribute my long-standing expertise.
Kozyrev, V., Staadt, R., Eysel, U. T., & Jancke, D. (2018). Tms-induced neuronal plasticity enables targeted remodeling of visual cortical maps. Proceedings of the National Academy of Sciences of the United States of America, 115(25), 6476–6481. https://doi.org/10.1073/pnas.1802798115
Vidyasagar, T. R., & Eysel, U. T. (2015). Origins of feature selectivities and maps in the mammalian primary visual cortex. Trends in Neurosciences, 38(8), 475–485. https://doi.org/10.1016/j.tins.2015.06.003
Kozyrev, V., Eysel, U. T., & Jancke, D. (2014). Voltage-sensitive dye imaging of transcranial magnetic stimulation-induced intracortical dynamics. Proceedings of the National Academy of Sciences of the United States of America, 111(37), 13553–13558. https://doi.org/10.1073/pnas.1405508111
Keck, T., Keller, G. B., Jacobsen, R. I., Eysel, U. T., Bonhoeffer, T., & Hübener, M. (2013). Synaptic scaling and homeostatic plasticity in the mouse visual cortex in vivo. Neuron, 80(2), 327–334. https://doi.org/10.1016/j.neuron.2013.08.018
Keck, T., Scheuss, V., Jacobsen, R. I., Wierenga, C. J., Eysel, U. T., Bonhoeffer, T., & Hübener, M. (2011). Loss of sensory input causes rapid structural changes of inhibitory neurons in adult mouse visual cortex. Neuron, 71(5), 869–882. https://doi.org/10.1016/j.neuron.2011.06.034
Palagina, G., Eysel, U. T., & Jancke, D. (2009). Strengthening of lateral activation in adult rat visual cortex after retinal lesions captured with voltage-sensitive dye imaging in vivo. Proceedings of the National Academy of Sciences of the United States of America, 106(21), 8743–8747. https://doi.org/10.1073/pnas.0900068106
Keck, T., Mrsic-Flogel, T. D., Vaz Afonso, M., Eysel, U. T., Bonhoeffer, T., & Hübener, M. (2008). Massive restructuring of neuronal circuits during functional reorganization of adult visual cortex. Nature Neuroscience, 11(10), 1162–1167. https://doi.org/10.1038/nn.2181
Giannikopoulos, D. V., & Eysel, U. T. (2006). Dynamics and specificity of cortical map reorganization after retinal lesions. Proceedings of the National Academy of Sciences of the United States of America, 103(28), 10805–10810. https://doi.org/10.1073/pnas.0604539103
Vidyasagar, T. R., Buzás, P., Kisvárday, Z. F., & Eysel, U. T. (1999). Release from inhibition reveals the visual past. Nature, 399(6735), 422–423. https://doi.org/10.1038/20836
Eysel, U. T. (1982). Functional reconnections without new axonal growth in a partially denervated visual relay nucleus. Nature, 299(5882), 442–444. https://doi.org/10.1038/299442a0
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Last update: Feb 28, 2024
